Pridinol Methanesulfonate Salt

Names

[ CAS No. ]:
6856-31-1

[ Name ]:
Pridinol Methanesulfonate Salt

[Synonym ]:
1,1-diphenyl-3-piperidin-1-ylpropan-1-ol,methanesulfonic acid

Biological Activity

[Description]:

Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Richter M, et al. Pharmacokinetics of oral pridinol: Results of a randomized, crossover bioequivalence trial in healthy subjects. Int J Clin Pharmacol Ther. 2021 Jun;59(6):471-477.

[2]. Duperray, B., et al. The fate of pridinol in the organism: Pharmacokinetics and distribution in animals. European Journal of Drug Metabolism and Pharmacokinetics 2, 121–130 (1977).

Chemical & Physical Properties

[ Boiling Point ]:
585.1ºC at 760 mmHg

[ Melting Point ]:
152.5-155ºC

[ Molecular Formula ]:
C₂₁H₂₉NO₄S

[ Molecular Weight ]:
391.52400

[ Flash Point ]:
307.6ºC

[ Exact Mass ]:
391.18200

[ PSA ]:
86.22000

[ LogP ]:
4.32120

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Anticataleptic effect of taurine: interaction with antiparkinsonian agents.

Pol. J. Pharmacol. Pharm. 39(4) , 329-35, (1987)

The influence of taurine on cataleptogenic effect of neuroleptics was investigated in male Wistar rats. It was found that taurine 900 micrograms/rat icv reduced significantly haloperidol or fluphenazi...

Suicide by multidrug ingestion: hypothesis on the role played by the self-administration of activated charcoal.

Am. J. Forensic Med. Pathol. 28(1) , 55-8, (2007)

A fatal suicidal ingestion of drugs, together with activated charcoal, is reported. The death occurred 31 hours after the self-administration. The autopsy revealed a large amount of gastric content th...

Pridinolum mesylate and neuroleptic malignant syndrome.

Am. J. Psychiatry 142(3) , 389-90, (1985)

Related Compounds

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