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Z-Gly-Pro-Arg-4MβNA acetate salt

Names

[ CAS No. ]:
66647-41-4

[ Name ]:
Z-Gly-Pro-Arg-4MβNA acetate salt

[Synonym ]:
Z-GLY-PRO-ARG-4MBNA COH
L-Argininamide, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-N-(4-methoxy-2-naphthalenyl)-
N-[(Benzyloxy)carbonyl]glycyl-L-prolyl-N-(4-methoxy-2-naphthyl)-L-argininamide

Biological Activity

[Description]:

Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). Free 4MβNA can be captured by 5-nitrosalicylaldehyde to produce an insoluble yellow fluorescent and marks the site of thrombin activity[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin
Research Areas >> Others

[References]

[1]. Bushi D, et al. A novel histochemical method for the visualization of thrombin activity in the nervous system. Neuroscience. 2016 Apr 21;320:93-104.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C32H39N7O6

[ Molecular Weight ]:
617.70

[ Exact Mass ]:
617.296204

[ LogP ]:
2.46

[ Index of Refraction ]:
1.646


Related Compounds