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Z-Gly-Pro-Arg-AMC · HCl

Names

[ CAS No. ]:
201928-42-9

[ Name ]:
Z-Gly-Pro-Arg-AMC · HCl

[Synonym ]:
Z-L-GLYCYL-L-PROLYL-L-ARGININE-7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
Z-GLY-PRO-ARG-MCA HYDROCHLORIDE
Z-Gly-Pro-Arg-AMC
BENZYLOXYCARBONYLGLYCYL-L-PROLYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE

Biological Activity

[Description]:

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[References]

[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292.  

[2]. Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401(1):91-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C31H38ClN7O7

[ Molecular Weight ]:
656.12900

[ Exact Mass ]:
655.25200

[ PSA ]:
208.95000

[ LogP ]:
4.49100

Related Compounds