tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite

Names

[ Name ]:
tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite

[Synonym ]:
[(CF3)2CHO]3P
Tris[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] phosphite
tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite
MFCD00192561
P(OiC3HF6)3
Tris(1,1,1,3,3,3-hexafluoro-2-propyl)phosphite

Chemical & Physical Properties

[ Density]:
1.69 g/mL at 25ºC(lit.)

[ Boiling Point ]:
130ºC(lit.)

[ Molecular Formula ]:
C₉H₃F₁₈O₃P

[ Molecular Weight ]:
532.06300

[ Flash Point ]:
44.5ºC

[ Exact Mass ]:
531.95300

[ PSA ]:
41.28000

[ LogP ]:
6.74270

[ Index of Refraction ]:
n20/D 1.300(lit.)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26;S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2920901900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2920901900

[ Summary ]:
2920901900 VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Solid phase synthesis of oligoribonucleotides using the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) group for the protection of the 2'-hydroxy functions and the H-phosphonate approach.

Nucleic Acids Res. 17(10) , 3689-97, (1989)

The solid phase synthesis of oligoribonucleotides using the H-phosphonate approach and the 1-[(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl (Ctmp) and dimethoxytrityl (DMTr) groups, respectively,...

Use of new phosphonylating and coupling agents in the synthesis of oligodeoxyribonucleotides via the H-phosphonate approach.

Nucleic Acids Res. 18(11) , 3327-31, (1990)

New phosphonylating and coupling agents for the synthesis of oligodeoxyribonucleotides via H-phosphonate approach have been developed. Tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite, prepared by the ...

Stereoselective propargylation mediated by a chiral metal cluster: reactions of [(propargylium)Co₂ (CO)₅{P(OR)₃}][BF₄] with carbon nucleophiles. Caffyn AJM and Nicholas KM.

J. Am. Chem. Soc. 115(14) , 6438-6439, (1993)