BEAUCAGE REAGENT

Names

[ Name ]:
BEAUCAGE REAGENT

[Synonym ]:
3H-1,2-Benzodithiol-3-one, 1,1-dioxide
1,1-dioxo-1λ<sup>6</sup>,2-benzodithiol-3-one
3H-1,2-Benzodithiol-3-one 1,1-dioxide
MFCD00132960
BEAUCAGE REAGENT
1,2-benzodithiol-3-one-1,1-dioxide

Biological Activity

[Description]:

Beaucage reagent is found to be potent in causing DNA cleavage.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Research Areas >> Cancer

[References]

[1]. Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent. Org Biomol Chem. 2010 Mar 21;8(6):1293-5.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
414.6±28.0 °C at 760 mmHg

[ Melting Point ]:
103-107 °C(lit.)

[ Molecular Formula ]:
C₇H₄O₃S₂

[ Molecular Weight ]:
200.235

[ Flash Point ]:
204.6±24.0 °C

[ Exact Mass ]:
199.960190

[ PSA ]:
84.89000

[ LogP ]:
1.13

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.690

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
3335

[ WGK Germany ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%