Diiodotyrosine

Names

[ CAS No. ]:
66-02-4

[ Name ]:
Diiodotyrosine

[Synonym ]:
cemiod
jodgorgon
UNII:ST90Q60YF3
DIT
2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
diiodotyrosine
3,5-Diiodotyrosine
3,5-Diiodo-4-hydroxy-b-phenylalanine
L-Tyr(3',5'-I2)
Itir
flaianina
Tyrosine, 3,5-diiodo-
4-hydroxy-3,5-diiodophenylalanine
apothyrin
D/L-3,5-Diiodotyrosine

Biological Activity

[Description]:

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid is a tyrosine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
2.4±0.1 g/cm3

[ Boiling Point ]:
410.5±45.0 °C at 760 mmHg

[ Melting Point ]:
213°C (rough estimate)

[ Molecular Formula ]:
C₉H₉I₂NO₃

[ Molecular Weight ]:
432.982

[ Flash Point ]:
202.1±28.7 °C

[ Exact Mass ]:
432.867157

[ PSA ]:
83.55000

[ LogP ]:
2.26

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.748

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2505000

CHEMICAL NAME :: Tyrosine, 3,5-diiodo-

CAS REGISTRY NUMBER :: 66-02-4

BEILSTEIN REFERENCE NO. :: 2218690

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H9-I2-N-O3

MOLECULAR WEIGHT :: 432.99

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1110 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(9),38,1990

Safety Information

[ HS Code ]:
29214980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29214980

Related Compounds

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