1-[4-hydroxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Names

[ Name ]:
1-[4-hydroxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
2',5'-Di-O-trityl-uridin
2',5'-bis-O-trityluridine
Enzastaurin Hydrochloride
2',5'-Bis-triphenylmethyl-pyrimidin-ribosid
2',5'-di-O-trityluridine
2',5'-ditrityluridine
O2',O5'-ditrityl-uridine

Biological Activity

[Description]:

2',5'-Bis-O-(triphenylMethyl)uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Molecular Formula ]:
C₄₇H₄₀N₂O₆

[ Molecular Weight ]:
728.83

[ Exact Mass ]:
728.28900

[ PSA ]:
102.78000

[ LogP ]:
7.18090

[ Index of Refraction ]:
1.705

1-[4-hydroxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream