cytidine 5'-(tetrahydrogen triphosphate)

Names

[ CAS No. ]:
65-47-4

[ Name ]:
cytidine 5'-(tetrahydrogen triphosphate)

[Synonym ]:
5'-CYTIDYLATE TRIPHOSPHATE
cytidine tetrahydrogen triphosphate
Cytidine 5'-(tetrahydrogen triphosphate)
Cytidine-5'-(tetrahydrogentriphosphate)
2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-
5'-CTP
cytosine-5'-triphosphate
cytidinetriphosphate
Cytidine 5′-triphosphate
cytidine-5'-triphosphate
Cytidine triphosphate
cytidine triphosphate-Na2
4-Amino-1-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-ribofuranosyl]pyrimidin-2(1H)-on
CTP
Cytidine, 5'-(tetrahydrogen triphosphate)

Biological Activity

[Description]:

Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83.

Chemical & Physical Properties

[ Density]:
2.5±0.1 g/cm3

[ Boiling Point ]:
849.2±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₆N₃O₁₄P₃

[ Molecular Weight ]:
483.156

[ Flash Point ]:
467.4±37.1 °C

[ Exact Mass ]:
482.984497

[ PSA ]:
299.85000

[ LogP ]:
-5.52

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.801

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA3914000

CHEMICAL NAME :: Cytidine, 5'-(tetrahydrogen triphosphate)

CAS REGISTRY NUMBER :: 65-47-4

BEILSTEIN REFERENCE NO. :: 0071190

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H16-N3-O14-P3

MOLECULAR WEIGHT :: 483.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 1 mmol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,52,1975

Safety Information

[ Safety Phrases ]:
S16-S26-S36/37/39

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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