Aminotrimethylene phosphonic acid
Names
[ CAS No. ]:
6419-19-8
[ Name ]:
Aminotrimethylene phosphonic acid
[Synonym ]:
Aminotri(methylene phosphonic acid)
nitrilotrimethylenephosphonic acid
N,N,N-triphosphonomethyl amine
Aminotris(methylphosphonic acid)
[Nitrilotris(methylene)]tris(phosphonic acid)
N_Tf
(Nitrilotris(methylene))triphosphonic acid
ATMP
ferrofos509
ATMPA
(nitrilotrimethanediyl)tris(phosphonic acid)
UNII-1Y702GD0FG
dowelll37
ntpo
Dequest 2000
BRIQUEST 301-50A
Aminotris(methanephosphonic acid)
Briquest 301
EINECS 229-146-5
MFCD00002138
Amino tris(methylene phosphonic acid)
Phosphonic acid, [nitrilotris(methylene)]tris-
Amino tris (methylene phosphonic acid)
Chemical & Physical Properties
[ Density]:
2.1±0.1 g/cm3
[ Boiling Point ]:
746.2±70.0 °C at 760 mmHg
[ Melting Point ]:
~215 °C (dec.)
[ Molecular Formula ]:
C3H12NO9P3
[ Molecular Weight ]:
299.050
[ Flash Point ]:
405.1±35.7 °C
[ Exact Mass ]:
298.972504
[ PSA ]:
205.26000
[ LogP ]:
-4.63
[ Vapour Pressure ]:
0.0±5.4 mmHg at 25°C
[ Index of Refraction ]:
1.610
[ Stability ]:
Stable. Incompatible with bases, strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SZ9860000
- CHEMICAL NAME :
- Phosphonic acid, (nitrilotris(methylene))tri-
- CAS REGISTRY NUMBER :
- 6419-19-8
- BEILSTEIN REFERENCE NO. :
- 1715724
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C3-H12-N-O9-P3
- MOLECULAR WEIGHT :
- 299.07
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),67,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >6310 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >2510 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- >2510 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1302 mg/kg/31D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - changes in sodium
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),67,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1717 No. of Facilities: 72 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 1279 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1717 No. of Facilities: 2426 (estimated) No. of Industries: 57 No. of Occupations: 33 No. of Employees: 38609 (estimated) No. of Female Employees: 2280 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S45-S36/37/39-S25
[ RIDADR ]:
3265
[ WGK Germany ]:
1
[ RTECS ]:
SZ9860000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Proc. Natl. Acad. Sci. U. S. A. 104 , 12282-7, (2007)
Conjugative transfer of plasmid DNA via close cell-cell junctions is the main route by which antibiotic resistance genes spread between bacterial strains. Relaxases are essential for conjugative trans...
Determination of phosphonates in natural waters by ion-pair high-performance liquid chromatography.J. Chromatogr. A. 773(1-2) , 139-46, (1997)
The paper describes a new method for the determination of phosphonates by ion-pair high-performance liquid chromatography. The phosphonates are complexed with Fe(III) and separated on a reversed-phase...
Adsorptive removal of nitrilotris(methylenephosphonic acid) antiscalant from membrane concentrates by iron-coated waste filtration sand.J. Hazard. Mater. 182(1-3) , 855-62, (2010)
Iron-coated waste filtration sand was investigated as a low-cost adsorbent for the removal of nitrilotris(methylenephosphonic acid) (NTMP) from membrane concentrates. The adsorption of this phosphonat...