Propargyl acetate

Names

[ CAS No. ]:
627-09-8

[ Name ]:
Propargyl acetate

[Synonym ]:
prop-2-ynyl acetate
MFCD00041601

Chemical & Physical Properties

[ Density]:
0.989

[ Boiling Point ]:
27-28ºC(lit.)

[ Molecular Formula ]:
C₅H₆O₂

[ Molecular Weight ]:
98.09990

[ Flash Point ]:
91 °F

[ Exact Mass ]:
98.03680

[ PSA ]:
26.30000

[ LogP ]:
0.18270

[ Appearance of Characters ]:
Liquid | Clear colorless

[ Index of Refraction ]:
n20/D 1.417(lit.)

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UK5076000

CHEMICAL NAME :: 2-Propyn-1-ol, acetate

CAS REGISTRY NUMBER :: 627-09-8

BEILSTEIN REFERENCE NO. :: 1742046

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H6-O2

MOLECULAR WEIGHT :: 98.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 520 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301-H312-H332

[ Precautionary Statements ]:
P280-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R10;R20/21/22

[ Safety Phrases ]:
S23-S36/37

[ RIDADR ]:
UN 1992 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UK5076000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(3)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Asymmetric synthesis of ?-hydroxy a, ß-unsaturated aldehydes via enantioselective direct addition of propargyl acetate to aldehydes El-Sayed E, et al.

Org. Lett. 3.19 , 3017-3020, (2001)

Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium Yang F, et al.

Tetrahedron Lett. 42.15 , 2839-2841, (2001)

Investigations on the ion transport mechanism in conducting polymer films Casalbore-Miceli G, et al.

Solid State Ionics 131.3 , 311-321, (2000)