FORMAMIDOXIME
Names
[ CAS No. ]:
624-82-8
[ Name ]:
FORMAMIDOXIME
[Synonym ]:
EINECS 210-865-8
carboxamidoxime
Aminoformaldehyde oxime
formamideoxime
N-hydroxycarboximidamide
n-hydroxy-methanimidamid
formamidoxim
n-hydroxymethanimidamide
isuretin
MFCD00008125
isouretin
Chemical & Physical Properties
[ Density]:
1.29g/cm3
[ Boiling Point ]:
224ºC at 760 mmHg
[ Melting Point ]:
112-115ºC(lit.)
[ Molecular Formula ]:
CH4N2O
[ Molecular Weight ]:
60.05530
[ Flash Point ]:
89.3ºC
[ Exact Mass ]:
60.03240
[ PSA ]:
58.61000
[ LogP ]:
0.06290
[ Index of Refraction ]:
1.471
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ4632000
- CHEMICAL NAME :
- Formamidoxime
- CAS REGISTRY NUMBER :
- 624-82-8
- LAST UPDATED :
- 199304
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C-H4-N2-O
- MOLECULAR WEIGHT :
- 60.07
- WISWESSER LINE NOTATION :
- QM1UM
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H351
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-40
[ Safety Phrases ]:
22-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
LQ4632000
[ HS Code ]:
2925290090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925290090
[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Cancer Res. 38(5) , 1291-5, (1978)
A series of amidoximes was prepared and evaluated for possible antitumor activity against L1210 leukemia. Three of the most active compounds in the L1210 system, formamidoxime, acetamidoxime, and 2-am...
Nitric oxide synthesis by tracheal smooth muscle cells by a nitric oxide synthase-independent pathway.Am. J. Physiol. 275(5 Pt 1) , L895-901, (1998)
Nitric oxide (NO) is known to be synthesized from L-arginine in a reaction catalyzed by NO synthase. Liver cytochrome P-450 enzymes also catalyze the oxidative cleavage of C==N bonds of compounds cont...
Effects of phenobarbital, beta-naphthoflavone, dexamethasone, and formamidoxime on the turnover of inducible microsomal proteins in cultured hepatocytes.J. Biol. Chem. 256(24) , 13079-84, (1981)
Microsomal proteins from cultured chick embryo hepatocytes were separated by polyacrylamide gel electrophoresis and their rate constants of degradation (Kd) were estimated using double isotope techniq...