Luciferase, firefly

Names

[ CAS No. ]:
61970-00-1

[ Name ]:
Luciferase, firefly

[Synonym ]:
Phenylalanine, N-benzoylglycyl-3-methyl-
N-Benzoylglycyl-3-methylphenylalanine
MFCD00131546

Biological Activity

[Description]:

Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

Peptides

[In Vitro]

Firefly luciferase is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. The enzyme catalyses the oxidation of firefly luciferin, requiring oxygen and ATP. Because of the requirement of ATP, firefly luciferases have been used extensively in biotechnology.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₀N₂O₄

[ Storage condition ]:
-20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22;S23;S26;S24/25;S36/S37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.

Biochem. Biophys. Res. Commun. 465 , 232-8, (2015)

A chemiluminescent method is proposed for quantitation of NO generation in cell cultures. The method is based on activation of soluble guanylyl cyclase by NO. The product of the guanylyl cyclase react...

Cation-dependent folding of 3' cap-independent translation elements facilitates interaction of a 17-nucleotide conserved sequence with eIF4G.

Nucleic Acids Res. 41(5) , 3398-413, (2013)

The 3'-untranslated regions of many plant viral RNAs contain cap-independent translation elements (CITEs) that drive translation initiation at the 5'-end of the mRNA. The barley yellow dwarf virus-lik...

Vimentin is a component of a complex that binds to the 5'-UTR of human heme-regulated eIF2α kinase mRNA and regulates its translation.

FEBS Lett. 587(5) , 474-80, (2013)

The human heme-regulated eIF2α kinase, also called the human heme-regulated inhibitor (hHRI) is significantly up-regulated particularly at the level of translation during stress. In this report we sho...