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Sipeimine

Names

[ CAS No. ]:
61825-98-7

[ Name ]:
Sipeimine

[Synonym ]:
Raddeamine,Sipeimine
(3β,5α)-3,20-Dihydroxycevan-6-one
Imperialine
Cevan-6-one, 3,20-dihydroxy-, (3β,5α)-
Sipeimine
3β,20-Dihydroxy-5α-cevan-6-one
RADDEAMINE
Imperialin
Kashmirine
(3β,5α,17β)-3,20-Dihydroxycevan-6-one
3,20-dihydroxycevan-6-one
peiminine
Cevan-6-one, 3,20-dihydroxy-, (3β,5α,17β)-
Verticinone

Biological Activity

[Description]:

Sipeimine is a natural product isolated from Fritillaria ussuriensis.IC50 value:Target:In vitro: Sipeimine can induce rejuvenation of a endophytic fungus; Sipeimine yield of the strain rejuvenated by adding 3% bulbus was effectively improved to 0.0563 mg/L and it is 21.9% higher than that of the initial strain [1].In vivo:

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Alkaloid
Research Areas >> Others

[References]

[1]. CUI Ying, et al. Rejuvenation of a Sipeimine-Producing Endophytic Fungus. Journal of Fungal Research, 2010-01

[2]. Yin H, et al. Sipeimine-producing endophytic fungus isolated from Fritillaria ussuriensis. Z Naturforsch C. 2008 Nov-Dec;63(11-12):789-93.


[Related Small Molecules]

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Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
567.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C27H43NO3

[ Molecular Weight ]:
429.635

[ Flash Point ]:
296.8±30.1 °C

[ Exact Mass ]:
429.324280

[ PSA ]:
60.77000

[ LogP ]:
3.90

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FL5830000
CHEMICAL NAME :
Cevan-6-one, 3,20-dihydroxy-, (3-beta,5-alpha,17-beta)-
CAS REGISTRY NUMBER :
61825-98-7
LAST UPDATED :
198912
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H43-N-O3
MOLECULAR WEIGHT :
429.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 3,249,1965

Safety Information

[ Safety Phrases ]:
24/25

[ WGK Germany ]:
3

[ RTECS ]:
FL5830000


Related Compounds

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