2-Hydroxyoctanoic acid

Names

[ CAS No. ]:
617-73-2

[ Name ]:
2-Hydroxyoctanoic acid

[Synonym ]:
a-Hydroxyoctanoic acid
Hexadecanoic acid,2-hydroxy
EINECS 210-524-3
2-hydroxy-n-octanoic acid
dl-A-hydroxypalmitic acid
2-hydroxypalmitic acid
hydroxyhexadecanoic acid
hydroxycaprylic Acid
α-Hydroxyoctanoic acid
DL-2-Hydroxycaprylic acid
DL-2-Hydroxyoctanoic acid
hydrogen carbonate (bicarbonate)
a-Hydroxycaprylic acid
D,L-2-hydroxyhexadecanoic acid
Octanoic acid, 2-hydroxy-
UNII:0R6X0G0S8A
monohydroxymonocarboxylic acid
HYDROXYPALMITIC ACID,2
2-HYDROXY C16:0 ACID
MFCD00014410
Hydroxypalmiticacid
2-Hydroxyoctanoic Acid
2-Hydroxycaprylic acid
Hydroxyoctanoic acid
(+/-)-2-HYDROXYHEXADECANOIC ACID

Biological Activity

[Description]:

2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. F Kasuya, et al. Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids. Biochem Pharmacol. 1996 Nov 22;52(10):1643-6.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
289.0±13.0 °C at 760 mmHg

[ Melting Point ]:
66-68 °C

[ Molecular Formula ]:
C₈H₁₆O₃

[ Molecular Weight ]:
160.21

[ Flash Point ]:
142.8±16.3 °C

[ Exact Mass ]:
160.109940

[ PSA ]:
57.53000

[ LogP ]:
1.96

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.463

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids.

Biochem. Pharmacol. 52 , 1643-1646, (1996)

Molecular characteristics of carboxylic acids were investigated for the ability to inhibit a purified medium chain acyl-CoA synthetase, using hexanoic acid as a substrate. Salicylic acid, 4-methylsali...

Determination of the enantiomers of alpha-hydroxy- and alpha-amino acids in capillary electrophoresis with contactless conductivity detection.

Electrophoresis 31 , 2044-2048, (2010)

The enantiomers of the anions of five alpha-hydroxy acids, namely lactic acid, alpha-hydroxybutyric acid, 2-hydroxycaproic acid, 2-hydroxyoctanoic acid and 2-hydroxydecanoic acid, as well as the two a...

3-Hydroxydicarboxylic aciduria due to long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency associated with sudden neonatal death: protective effect of medium-chain triglyceride treatment.

Eur. J. Pediatr. 150(3) , 190-5, (1991)

Two siblings were found to be affected by long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, one of which died suddenly and unexpectedly on the 3rd day of life suffering from extreme hypoketotic h...

Related Compounds

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