4-Chloronaphthalen-1-ol

Names

[ CAS No. ]:
604-44-4

[ Name ]:
4-Chloronaphthalen-1-ol

[Synonym ]:
4-Chloro-α-naphthol
1-Chloro-4-hydroxynaphthalene
4ClN
1-Naphthalenol, 4-chloro-
4-chloronaphthalen-1-ol
EINECS 210-068-5
MFCD00003974
4-Chloro-1-naphthol

Biological Activity

[Description]:

4-Chloronaphthalen-1-ol is a substrate of horseradish peroxidase. 4-Chloronaphthalen-1-ol can be used to visualize protein bands in western blotting[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Elias JM, et, al. A rapid, sensitive myeloperoxidase stain using 4-chloro-1-naphthol. Am J Clin Pathol. 1980 Jun;73(6):797-9.

[2]. Hou L, et, al. Graphene oxide-labeled sandwich-type impedimetric immunoassay with sensitive enhancement based on enzymatic 4-chloro-1-naphthol oxidation. Biosens Bioelectron. 2013 Sep 15;47:149-56.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
332.1±15.0 °C at 760 mmHg

[ Melting Point ]:
118-121 °C(lit.)

[ Molecular Formula ]:
C₁₀H₇ClO

[ Molecular Weight ]:
178.615

[ Flash Point ]:
154.6±20.4 °C

[ Exact Mass ]:
178.018539

[ PSA ]:
20.23000

[ LogP ]:
3.66

[ Appearance of Characters ]:
tablets (~32 mg each)

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.684

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: 50 mg/mL, clear, colorless to very faintly yellow

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S45-S36/37

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2908199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

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