1-Methoxynapthalene

Names

[ Name ]:
1-Methoxynapthalene

[Synonym ]:
Naphthalene, 1-methoxy-
1-naphthol methyl ether
Naphthalene,1-methoxy
EINECS 218-696-1
MFCD00003924
1-Methoxynapthalene
methoxy-naphthalene
1-naphthyl methyl ether
Methyl 1-naphthyl ether
α-Methoxynaphthalene
methyl naphthalen-1-yl ether
methyl naphthyl ether
1-methoxy naphthalene
1-Methoxynaphthalene

Biological Activity

[Description]:

1-Methoxynaphthalene is used as the substrate to investigate the activity of cytochrome c peroxidase (CcP). 1-Methoxynaphthalene also can be used to synthesize prenyl naphthalen-ols[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Erman JE, et, al. Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants: hydroxylation of 1-methoxynaphthalene. BMC Biochem. 2013 Jul 30;14:19.

[2]. Shindo K, et, al. Production of novel antioxidative prenyl naphthalen-ols by combinational bioconversion with dioxygenase PhnA1A2A3A4 and prenyltransferase NphB or SCO7190. Biosci Biotechnol Biochem. 2011;75(3):505-10.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
268.3±9.0 °C at 760 mmHg

[ Melting Point ]:
5 °C

[ Molecular Formula ]:
C₁₁H₁₀O

[ Molecular Weight ]:
158.197

[ Flash Point ]:
102.3±8.0 °C

[ Exact Mass ]:
158.073166

[ PSA ]:
9.23000

[ LogP ]:
3.36

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Water Solubility ]:
immiscible

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QJ9465500

[ HS Code ]:
29093090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Production of novel antioxidative prenyl naphthalen-ols by combinational bioconversion with dioxygenase PhnA1A2A3A4 and prenyltransferase NphB or SCO7190.

Biosci. Biotechnol. Biochem. 75(3) , 505-10, (2011)

We performed combinational bioconversion of substituted naphthalenes with PhnA1A2A3A4 (an aromatic dihydroxylating dioxygenase from marine bacterium Cycloclasticus sp. strain A5) and prenyltransferase...

Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants: hydroxylation of 1-methoxynaphthalene.

BMC Biochem. 14(1) , 19, (2013)

The cytochrome P450s are monooxygenases that insert oxygen functionalities into a wide variety of organic substrates with high selectivity. There is interest in developing efficient catalysts based on...