N-(3-Fluoranthyl)maleimide

Names

[ Name ]:
N-(3-Fluoranthyl)maleimide

[Synonym ]:
N-(3-fluoroanthyl)maleimide
1-(Fluoranthen-3-yl)-1H-pyrrole-2,5-dione
MFCD00042618
N-(3-Fluoranthyl)maleimide
EINECS 262-197-1

Biological Activity

[Description]:

N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Y Miyamoto, et al. Interaction between cell-binding domain and extracellular matrix-binding domain of fibronectin determined by fluorescence depolarization. Biochim Biophys Acta. 1988 Apr 14;953(3):306-13

Chemical & Physical Properties

[ Density]:
1.466g/cm3

[ Boiling Point ]:
526.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₁NO₂

[ Molecular Weight ]:
297.30700

[ Flash Point ]:
256.1ºC

[ Exact Mass ]:
297.07900

[ PSA ]:
37.38000

[ LogP ]:
3.98160

[ Index of Refraction ]:
1.875

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing.

PLoS ONE 10(1) , e0116929, (2015)

Accumulating evidence has demonstrated the importance of alternative splicing in various physiological processes, including the development of different diseases. CDC-like kinases (CLKs) and serine-ar...

Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls.

PLoS ONE 9(9) , e108336, (2014)

Mutations in the ABC transporter ABCC6 were recently identified as cause of Pseudoxanthoma elasticum (PXE), a rare genetic disorder characterized by progressive mineralization of elastic fibers. We us...

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.

J. Clin. Invest. 125(2) , 831-45, (2015)

Expansion of the polyglutamine (polyQ) tract within the androgen receptor (AR) causes neuromuscular degeneration in individuals with spinobulbar muscular atrophy (SBMA). PolyQ AR has diminished transc...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.