Fentonium

Names

[ Name ]:
Fentonium

[Synonym ]:
Fentonio bromuro [DCIT]
Ulcesium
Z 326
Fentonii bromidum [INN-Latin]
Bromure de fentonium [INN-French]
FA 402
Ketoscilium
Fentonium bromide
Phentonium bromide

Biological Activity

[Description]:

Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vivo]

Fentonium bromide (1 mg/kg, i.v.) is an effective antagonist of gastric secretion in rats[1]. Fentonium bromide (phentonium, 1 mg/kg, i.p.) prevents stress ulcers in rats[1]. Animal Model: Bethanechol-, pentagastrin-, and caerulein-induced gastric secretion in rats[1] Dosage: 1 mg/kg Administration: Intravenous injection (i.v.) Result: Inhibited gastric acid secretion. Animal Model: Rats[2] Dosage: 1 mg/kg Administration: Intraperitoneal injection (i.p.) Result: Decreased both the number of pre-ulceral lesions and the number of gastroduodenal ulcers in comparison with untreated controls.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₄BrNO₄

[ Molecular Weight ]:
564.51000

[ Exact Mass ]:
563.16700

[ PSA ]:
63.60000

[ LogP ]:
1.95840

Related Compounds

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