SB 737050A

Names

[ Name ]:
SB 737050A

[Synonym ]:
4-(5-Chloro-2-thienyl)-N-(8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)benzenesulfonamide
Benzenesulfonamide, 4-(5-chloro-2-thienyl)-N-(2,3,4,5-tetrahydro-8-methoxy-3-methyl-1H-3-benzazepin-7-yl)-

Biological Activity

[Description]:

SB-737050A is a potent 5-HT6 antagonist to prevent relapse into addiction[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT6 Receptor

[References]

[1]. Natasja M.W.J. De Bruin, et al. Use of 5-ht6 antagonists to prevent relapse into addiction. US20080171779A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
602.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₃ClN₂O₃S₂

[ Molecular Weight ]:
463.01

[ Flash Point ]:
318.2±34.3 °C

[ Exact Mass ]:
462.083862

[ LogP ]:
5.09

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.632

Related Compounds

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