1-(2-hydroxy-1-naphthyl)ethan-1-one

Names

[ CAS No. ]:
574-19-6

[ Name ]:
1-(2-hydroxy-1-naphthyl)ethan-1-one

[Synonym ]:
1-(2-hydroxynaphthalen-1-yl)ethanone
EINECS 209-369-4
MFCD00012131

Biological Activity

[Description]:

2'-Hydroxy-1'-acetonaphthone is a Schiff base used as pharmaceutical intermediates[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Wojciech Schilf, et al.Intramolecular hydrogen bond investigations in Schiff bases derivatives of 2-hydroxy-1-naphthaldehyde and 2-hydroxy-1-acetonaphthone in CDCl3 solution and in the solid state by NMR methods. Journal of Molecular Structure, Volumes 602–603, 9 January 2002, Pages 41-47.

Chemical & Physical Properties

[ Density]:
1.213 g/cm3

[ Boiling Point ]:
334.9ºC at 760 mmHg

[ Melting Point ]:
61ºC to 66ºC

[ Molecular Formula ]:
C₁₂H₁₀O₂

[ Molecular Weight ]:
186.20700

[ Flash Point ]:
130-132°C/2mm

[ Exact Mass ]:
186.06800

[ PSA ]:
37.30000

[ LogP ]:
2.74800

[ Index of Refraction ]:
1.65

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Intramolecular hydrogen bond investigations in Schiff bases derivatives of 2-hydroxy-1-naphthaldehyde and 2-hydroxy-1-acetonaphthone in CDCl< sub> 3</sub> solution and in the solid state by NMR methods. Schilf W, et al.

J. Mol. Struct. 602 , 41-7, (2002)