Fructose

Names

[ CAS No. ]:
57-48-7

[ Name ]:
Fructose

[Synonym ]:
(2R,3S,4S,5R)-2,5-bis(hydroxymethyl)oxolane-2,3,4-triol
D(-)-Fructose
D-Fructose
β-d-Fructose
D-(-)-Fructose
Levulose
EINECS 200-333-3
Fructose [JAN]
UNII:02T79V874P
Fructose, D-
(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanon
(3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one
Levugen
Fruit sugar
beta-D-fructofuranose
D-(-)-levulose
Fructose (JP15/USP)
b-D-Fructose
DSSTox_CID_3081
fructose powder
arabino-2-Hexulose
1,3,4,5,6-pentahydroxyl-2-hexanone
D-Levulose
(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanone
Frutabs
δ-Fructose
Fructooligosaccharides
MFCD00148910
Fructose
β-δ-fructose
keto-D-fructose
D-fructofuranose
β-Fruit sugar
D-arabino-Hexulose
Furucton
β-D-arabino-Hexulose
β-Levulose
keto D-fructose
Laevosan
Laevoral
Fructose, furanose form
Fructosteril

Biological Activity

[Description]:

D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
551.7±50.0 °C at 760 mmHg

[ Melting Point ]:
119-122 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₁₂O₆

[ Molecular Weight ]:
180.156

[ Flash Point ]:
301.5±26.6 °C

[ Exact Mass ]:
180.063385

[ PSA ]:
118.22000

[ LogP ]:
-1.63

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Water Solubility ]:
3750 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LS7120000

CHEMICAL NAME :: D-Fructose

CAS REGISTRY NUMBER :: 57-48-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H12-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A132-656 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 119 mg/kg/14D-I

TOXIC EFFECTS :: Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A132-656

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LS7120000

[ HS Code ]:
17025000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 17025000

Articles

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

L-lactate production from biodiesel-derived crude glycerol by metabolically engineered Enterococcus faecalis: cytotoxic evaluation of biodiesel waste and development of a glycerol-inducible gene expression system.

Appl. Environ. Microbiol. 81(6) , 2082-9, (2015)

Biodiesel waste is a by-product of the biodiesel production process that contains a large amount of crude glycerol. To reuse the crude glycerol, a novel bioconversion process using Enterococcus faecal...

Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor.

PLoS ONE 9(12) , e112263, (2014)

The transcriptional regulator HAP4, induced by respiratory substrates, is involved in the balance between fermentation and respiration in S. cerevisiae. We identified putative orthologues of the Hap4 ...