p-Methoxybenzyl isocyanate

Names

[ Name ]:
p-Methoxybenzyl isocyanate

[Synonym ]:
MFCD00673064
1-(Isocyanatomethyl)-4-methoxybenzene
p-Methoxybenzyl isocyanate
Benzene, 1-(isocyanatomethyl)-4-methoxy-
4-(Isocyanatomethyl)phenyl methyl ether

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
249.9±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₉NO₂

[ Molecular Weight ]:
163.173

[ Flash Point ]:
112.6±17.1 °C

[ Exact Mass ]:
163.063324

[ PSA ]:
38.66000

[ LogP ]:
2.52

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.507

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H334-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38;R42

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 2206PSN1B 6.1 / PGIII

[ WGK Germany ]:
3

[ HS Code ]:
2929109000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Discovery of nitroaryl urea derivatives with antiproliferative properties.

J. Enzyme Inhib. Med. Chem. , 1-11, (2015)

A series of urea derivatives bearing nitroaryl moiety has been synthesized and assayed for their potential antiproliferative activities. Some of the tested compounds displayed activity in RK33 larynge...

The first synthesis of a novel 5:7:5-fused diimidazodiazepine ring system and some of its chemical properties.

Org. Lett. 10(20) , 4681-4, (2008)

The first synthesis of a novel 5:7:5-fused heterocyclic ring system, a diimidazodiazepine, is reported. The propensity of the ring system to undergo facile, acid-catalyzed nucleophilic addition reacti...

Total synthesis of (+)-batzelladine A and (-)-batzelladine D via [4 + 2]-annulation of vinyl carbodiimides with N-alkyl imines.

J. Am. Chem. Soc. 128 , 13255, (2006)

A diastereoselective [4 + 2]-annulation of vinyl carbodiimides with chiral N-alkyl imines has been developed to access the stereochemically rich polycyclic guanidine cores of the batzelladine alkaloid...