Lewis-a trisaccharide

Names

[ Name ]:
Lewis-a trisaccharide

[Synonym ]:
lewis a trisaccharide

Biological Activity

[Description]:

Lewis a trisaccharide (Lewis a) is a trisaccharide that has been found to be present in the glycan structures of spermatozoa. Lewis a trisaccharide also is a major component of the glycan structures on the surface of HL-60 cells[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. A C Fitchette-Lainé, et al. N-glycans harboring the Lewis a epitope are expressed at the surface of plant cells. Plant J. 1997 Dec;12(6):1411-7.

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Boiling Point ]:
977.2ºC at 760mmHg

[ Melting Point ]:
160-162ºC

[ Molecular Formula ]:
C₂₀H₃₅NO₁₅

[ Molecular Weight ]:
529.49000

[ Flash Point ]:
544.8ºC

[ Exact Mass ]:
529.20100

[ PSA ]:
257.32000

[ Index of Refraction ]:
1.632

[ Storage condition ]:
2-8°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

N-glycans harboring the Lewis a epitope are expressed at the surface of plant cells.

Plant J. 12(6) , 1411-7, (1997)

In plants, N-linked glycans are processed in the Golgi apparatus to complex-type N-glycans of limited size containing a beta(1,2)-xylose and/or an alpha(1,3)-fucose residue. Larger mono- and bi-antenn...

Studies on the three-dimensional behaviour of the selectin ligands Lewis(a) and sulphated Lewis(a) using NMR spectroscopy and molecular dynamics simulations.

Glycobiology 4(1) , 49-57, (1994)

Sulphated blood group Lewis(a)/Lewis(x) (Le(a)/Le(x)) type sequences, with sulphate at the 3-position of galactose, have emerged as potent ligands for the endothelial adhesion molecule E-selectin and ...

CA-S27: a novel Lewis a associated carbohydrate epitope is diagnostic and prognostic for cholangiocarcinoma.

Cancer Sci. 104 , 1278-1284, (2013)

Early and specific diagnosis is critical for treatment of cholangiocarcinoma (CCA). In this study, a carbohydrate antigen-S27 (CA-S27) monoclonal antibody (mAb) was established using pooled CCA tissue...

Related Compounds

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