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ACTH (4-9)

Names

[ CAS No. ]:
56236-83-0

[ Name ]:
ACTH (4-9)

[Synonym ]:
acth (4 - 9)

Biological Activity

[Description]:

ACTH (4-9) is an adrenocorticotropic hormone (ACTH) fragment. ACTH (4-9) is the 4-9 sequence fragment of ACTH[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vivo]

ACTH (4-9) (1 mg/kg; i.h.; 孕鼠或新生幼崽) 抑制晚年相关的行为表现能力[1]。 Animal Model: Pregnant female mouse or newborn pups[1] Dosage: 1 mg/kg Administration: Subcutaneous injection Result: Inhibited learning/memory task performance m males and females mouse.

[References]

[1]. Honour LC, et, al. Pre- and postnatally administered ACTH, Organon 2766 and CRF facilitate or inhibit active avoidance task performance in young adult mice. Peptides. 1988 Jul-Aug;9(4):745-50.   

[2]. Sekita-Krzak J, et, al. Protective effects of ACTH (4-9) in degeneration of hippocampal nerve cells caused by dexamethasone: ultrastructural studies. Ann Univ Mariae Curie Sklodowska Med. 2002;57(2):233-8.   

Chemical & Physical Properties

[ Molecular Formula ]:
C42H56N12O9S

[ Molecular Weight ]:
905.03400

[ Exact Mass ]:
904.40100

[ PSA ]:
377.79000

[ LogP ]:
3.48170

Related Compounds