<Suppliers Price>

ACTH (4-11)

Names

[ CAS No. ]:
67224-41-3

[ Name ]:
ACTH (4-11)

[Synonym ]:
Methionyl-glutamyl-histidinyl-phenylalanyl-argininyl-tryptophanyl-glycinyl-lysine
MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS
H-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-OH
MEHFRWGK
ADRENOCORTICOTROPIC HORMONE FRAGMENT 4-11
MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS

Biological Activity

[Description]:

ACTH (4-11), an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM).

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease
Peptides

[In Vitro]

α-melanocyte stimulating hormone (MSH) induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. Adrenocorticotropic hormone (ACTH) possesses the same amino acid sequence as MSH does. α-MSH induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. ACTH (4-11) loses almost all activity for the binding to melanocortin receptor 1 (MC1R)[1].

[References]

[1]. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.46 g/cm3

[ Molecular Formula ]:
C50H71N15O11S

[ Molecular Weight ]:
1090.26000

[ Exact Mass ]:
1089.52000

[ PSA ]:
462.01000

[ LogP ]:
3.69380

[ Index of Refraction ]:
1.682

[ Storage condition ]:
2-8℃

Related Compounds