H-Sar-OtBu.HCl

Names

[ Name ]:
H-Sar-OtBu.HCl

[Synonym ]:
tert-Butyl sarcosinate hydrochloride
Glycine, N-methyl-, 1,1-dimethylethyl ester, hydrochloride (1:1)
Sarcosine tert-butyl ester.HCl;; tert-butyl sarcosinate.HCl
tert-Butyl N-methylglycinate hydrochloride (1:1)
MFCD00080936
2-Methyl-2-propanyl N-methylglycinate hydrochloride (1:1)
H-Sar-OtBu·HCl
H-Sar-OtBu.HCl

Biological Activity

[Description]:

tert-Butyl 2-(methylamino)acetate is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
0.928g/cm3

[ Boiling Point ]:
168.5ºC at 760 mmHg

[ Melting Point ]:
137-141 °C (dec.)

[ Molecular Formula ]:
C₇H₁₆ClNO₂

[ Molecular Weight ]:
181.660

[ Flash Point ]:
55.7ºC

[ Exact Mass ]:
181.086960

[ PSA ]:
38.33000

[ LogP ]:
1.74040

[ Index of Refraction ]:
1.422

[ Storage condition ]:
-15°C

Safety Information

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: Nitric oxide-donor naproxen prodrugs. Ranatunge RR, et al.

Bioorg. Med. Chem. 14(8) , 2589, (2006)