1-Octacosanol

Names

[ CAS No. ]:
557-61-9

[ Name ]:
1-Octacosanol

[Synonym ]:
EINECS 209-181-2
n-octacosanol
Octacosan-1-ol
1-Octacosanol
MFCD00044770
OCTACOSANOL,1
octacosanol
Cluytyl alcohol
Policosanol
octacosyl alcohol

Biological Activity

[Description]:

1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Gao W, et al. High-performance thin-layer chromatography for quantification of 1-octacosanol in Antarctic krill (Euphausia superba Dana). J Chromatogr Sci. 2015 May-Jun;53(5):811-5.

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
428.1±8.0 °C at 760 mmHg

[ Melting Point ]:
81-83°C

[ Molecular Formula ]:
C₂₈H₅₈O

[ Molecular Weight ]:
410.759

[ Flash Point ]:
135.3±6.0 °C

[ Exact Mass ]:
410.448761

[ PSA ]:
20.23000

[ LogP ]:
13.63

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.458

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Light-sensitive. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
<0.1 g/100 mL at 21.5 ºC

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ Packaging Group ]:
I; II; III

[ HS Code ]:
2905199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905199090

[ Summary ]:
2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

In vitro and in vivo study of octacosanol metabolism.

Arch. Med. Res. 36(2) , 113-9, (2005)

Policosanol is a mixture of very-long-chain aliphatic alcohols purified from sugar cane wax with cholesterol-lowering effects, whose main component is octacosanol. Scarce data about the metabolism of ...

Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi.

Eur. J. Med. Chem. 50 , 230-5, (2012)

Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol frac...

Contents and compositions of policosanols in green tea (Camellia sinensis) leaves.

Food Chem. 204 , 94-101, (2016)

Policosanol (PC) is a mixture of health promoting bioactive long-chain aliphatic alcohols. Here, we report that green tea (Camellia sinensis) leaves are the exceptionally rich plant-sources of PC. You...