D-Allylglycine

Names

[ Name ]:
D-Allylglycine

[Synonym ]:
D-a-Allylglycine
4-Pentenoic acid, 2-amino-, (R)-
(R)-allylglycine
(R)-α-Allylglycine
3-VINYL-D-ALANINE
H-ALLYL-D-GLYCINE
(R)-2-Allylglycine
(R)-2-amino-4-pentenoic acid
H-D-Gly(Ally)-OH
(2R)-2-Amino-4-pentenoic acid
H-D-ALGLY-OH
(R)-2-Aminopent-4-enoic acid
(2R)-2-aminopent-4-enoic acid
4-Pentenoic acid, 2-amino-, (2R)-
D-Allyiglycine
D-C-ALLYLGLYCINE
MFCD00063104
H-D-GLY(ALLYL)-OH
(R)-2-allyl-Gly
D-2-Amino-4-pentenoic acid

Biological Activity

[Description]:

H-D-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
230.9±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
93.5±25.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
0.26

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.484

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
22-24/25-36-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

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J. Med. Chem. 52 , 5093-107, (2009)

Retaining agonistic activity at the glycine coagonist site of the NMDA receptor in molecules derived from glycine or d-serine has proven to be difficult because in the vicinity of the alpha-amino acid...

In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats.

Neuropharmacology 62 , 907-913, (2012)

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Chem. Biol. Drug Des. 74 , 329-334, (2009)

The opioid peptide H-Tyr-c[D-Cys-Phe-Phe-Cys]NH(2) cyclized via a methylene dithiother is a potent and selective mu opioid agonist (Przydial M.J. et al., J Peptide Res, 66, 2005, 255). Dicarba analogu...