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N-Glycidylphthalimide

Names

[ CAS No. ]:
5455-98-1

[ Name ]:
N-Glycidylphthalimide

[Synonym ]:
N-Glycidylphthalimide
1H-Isoindole-1,3(2H)-dione, 2-(oxiranylmethyl)-
EINECS 226-710-2
2-(oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione
n-(2,3-epoxypropyl)phthalimide
2-(2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione
N-Glycidyl phthalimide
MFCD00005896
N-(2,3-Epoxypropyl)-o-Phthalimide
2-((OXIRAN-2-YL)METHYL)ISOINDOLINE-1,3-DIONE

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
347.4±15.0 °C at 760 mmHg

[ Melting Point ]:
92-98 °C(lit.)

[ Molecular Formula ]:
C11H9NO3

[ Molecular Weight ]:
203.194

[ Flash Point ]:
163.9±20.4 °C

[ Exact Mass ]:
203.058243

[ PSA ]:
49.91000

[ LogP ]:
1.60

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.649

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI4950000
CHEMICAL NAME :
Phthalimide, N-(2,3-epoxypropyl)-
CAS REGISTRY NUMBER :
5455-98-1
BEILSTEIN REFERENCE NO. :
0171277
LAST UPDATED :
199712
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C11-H9-N-O3
MOLECULAR WEIGHT :
203.21
WISWESSER LINE NOTATION :
T56 BVNVJ C1- BT3OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4700 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4400 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 68,251,1979

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
TI4950000

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds

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