2-Methyl-1H-indole-3-carbaldehyde
Names
[ CAS No. ]:
5416-80-8
[ Name ]:
2-Methyl-1H-indole-3-carbaldehyde
[Synonym ]:
Indole-3-carboxaldehyde, 2-methyl-
3-FORMYL-2-METHYLINDOLE
2-Methylindole-3-carboxaldehyde
2-Methyl-1H-indole-3-carbaldehyde
MFCD00012077
EINECS 226-512-6
1H-Indole-3-carboxaldehyde, 2-methyl-
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
344.3±22.0 °C at 760 mmHg
[ Melting Point ]:
200-201 °C(lit.)
[ Molecular Formula ]:
C10H9NO
[ Molecular Weight ]:
159.185
[ Flash Point ]:
169.9±29.8 °C
[ Exact Mass ]:
159.068420
[ PSA ]:
32.86000
[ LogP ]:
2.14
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.699
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Med. Chem. 92 , 776-83, (2015)
Streptochlorin, first isolated as a new antibiotic in 1988 from the lipophilic extracts of the mycelium of a Streptomyces sp, is an indole natural products with a variety of biological activities. Bas...
Functionalization of benzylic C(sp(3))-H bonds of heteroaryl aldehydes through N-heterocyclic carbene organocatalysis.Angew. Chem. Int. Ed. Engl. 52(42) , 11134-7, (2013)
Aryl aldehyde activation: Oxidative activation of 2-methylindole-3-carboxaldehyde (I) through N-heterocyclic carbene (NHC) organocatalysis generates heterocyclic ortho-quinodimethane (II) as a key int...
(2-Methyl-1-phenyl-sulfonyl-1H-indol-3-yl)methanol.Acta Crystallogr. Sect. E Struct. Rep. Online 64(2) , o542-o542, (2008)
In the title compound, C(16)H(15)NO(3)S, the plane of the phenyl ring forms a dihedral angle of 80.37 (8)° with the indole ring system. The crystal packing is stabilized by weak O-H⋯O hydrogen bonds w...