reptoside

Names

[ Name ]:
reptoside

[Synonym ]:
Acetic acid (1S,4aS,7S)-4a-hydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-7-yl ester

Biological Activity

[Description]:

Reptoside, an iridoid glucoside, is a DNA damaging active agent. Reptoside has strong interactions with Trp352 and Tyr335 in AKT1[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> Akt

[References]

[1]. Gören AC, et, al. DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside. Nat Prod Res. 2005 Jul;19(5):457-60.

[2]. Wang T, et, al. Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis. Sci Rep. 2022 May 6;12(1):7430.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₆O₁₀

[ Molecular Weight ]:
390.38

[ Exact Mass ]:
390.15300

[ PSA ]:
155.14000

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.