53839-03-5

53839-03-5 structure

Name: reptoside
Chemical Name: reptoside
CAS Number: 53839-03-5
Molecular Formula: C₁₇H₂₆O₁₀
Molecular Weight: 390.38
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2018-05-26 21:50:59
Modify Date: 2024-01-06 18:07:54
Reptoside, an iridoid glucoside, is a DNA damaging active agent. Reptoside has strong interactions with Trp352 and Tyr335 in AKT1[1].

Name	reptoside
Synonyms	Acetic acid (1S,4aS,7S)-4a-hydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-7-yl ester

Description	Reptoside, an iridoid glucoside, is a DNA damaging active agent. Reptoside has strong interactions with Trp352 and Tyr335 in AKT1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Gören AC, et, al. DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside. Nat Prod Res. 2005 Jul;19(5):457-60. [2]. Wang T, et, al. Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis. Sci Rep. 2022 May 6;12(1):7430.