(2-Aminophenyl)methanol
Names
[ CAS No. ]:
5344-90-1
[ Name ]:
(2-Aminophenyl)methanol
[Synonym ]:
Benzenemethanol, 2-amino-
2-Aminobenzyl alcohol
MFCD00007749
EINECS 226-293-7
2-Hydroxymethylaniline
(2-Aminophenyl)methanol
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
275.0±0.0 °C at 760 mmHg
[ Melting Point ]:
81-83 °C(lit.)
[ Molecular Formula ]:
C7H9NO
[ Molecular Weight ]:
123.15
[ Flash Point ]:
126.3±20.4 °C
[ Exact Mass ]:
123.068413
[ PSA ]:
46.25000
[ LogP ]:
-0.25
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.617
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DN3155000
- CHEMICAL NAME :
- Benzyl alcohol, o-amino-
- CAS REGISTRY NUMBER :
- 5344-90-1
- BEILSTEIN REFERENCE NO. :
- 1072211
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H9-N-O
- MOLECULAR WEIGHT :
- 123.17
- WISWESSER LINE NOTATION :
- ZR B1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 8 mmol/L
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 52,203,1990
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DN3155000
[ HS Code ]:
29221980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Med. Chem. 48(25) , 8079-86, (2005)
Two new classes of lipophilic prodrugs of the antiviral active phosphonate 9-[2-phosphonomethoxyethyl]adenine (PMEA 1) have been prepared and were studied with regard to their hydrolysis properties an...
Heterotrimetallic RuMnMn species on a hydrotalcite surface as highly efficient heterogeneous catalysts for liquid-phase oxidation of alcohols with molecular oxygen.Angew. Chem. Int. Ed. Engl. 44(22) , 3423-6, (2005)
Facile intramolecular nucleophilic attack by alkoxide ions on ethyl and p-nitrophenyl carbamates.
J. Am. Chem. Soc. 95(11) , 3786-3790, (1973)