D-Ribonolactone

Names

[ Name ]:
D-Ribonolactone

[Synonym ]:
D(+)-Ribonic acid gamma-lactone
D-Ribono-1,4-lactone
3,4-Dihydroxy-5-(hydroxymethyl)dihydro-2(3H)-furanone
3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (non-preferred name)
MFCD00063241
.γ.-Lactone of ribonic acid
D-(+)-Ribonic γ-lactone
EINECS 226-256-5
D-(+)-Ribono-1,4-lactone

Biological Activity

[Description]:

D-Ribonolactone is sugar lactone and an inhibitor of β-galactosidase of Escherichia coli with a Ki of 26 mM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Human Endogenous Metabolite

[In Vitro]

Ki: 26 mM (β-galactosidase)

[References]

[1]. Huber RE, et al. Strong inhibitory effect of furanoses and sugar lactones on beta-galactosidase Escherichia coli. Biochemistry. 1987 Mar 24;26(6):1526-31.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
364.3±11.0 °C at 760 mmHg

[ Melting Point ]:
83-85ºC

[ Molecular Formula ]:
C₅H₈O₅

[ Molecular Weight ]:
148.114

[ Flash Point ]:
162.8±12.8 °C

[ Exact Mass ]:
148.037170

[ PSA ]:
86.99000

[ LogP ]:
-2.47

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.581

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%