N4-Bz-2'-OMe-rC

Names

[ Name ]:
N4-Bz-2'-OMe-rC

[Synonym ]:
N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
N4-Bz-2'-OMe-rC

Biological Activity

[Description]:

N4-Benzoyl-2’-O-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Melting Point ]:
174-175ºC

[ Molecular Formula ]:
C₁₇H₁₉N₃O₆

[ Molecular Weight ]:
361.35

[ Exact Mass ]:
361.12700

[ PSA ]:
122.91000

[ Appearance of Characters ]:
Powder | White to Pale Yellow

[ Index of Refraction ]:
1.659

Safety Information

[ Hazard Codes ]:
Xi

N4-Bz-2'-OMe-rC

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Related Compounds