Isopteropodine

Names

[ Name ]:
Isopteropodine

[Synonym ]:
Isopteropodine

Biological Activity

[Description]:

Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Signaling Pathways >> GPCR/G Protein >> mAChR

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT2 Receptor

[References]

[1]. Tai-Hyun Kang,etc. Pteropodine and isopteropodine positively modulate the function of rat muscarinic M1 and 5-HT2 receptors expressed in Xenopus oocyte. European Journal of Pharmacology, Volume 444, Issues 1–2, 2002, Pages 39-45, ISSN 0014-2999,

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
555.2ºC at 760 mmHg

[ Melting Point ]:
209-211 °C

[ Molecular Formula ]:
C₂₁H₂₄N₂O₄

[ Molecular Weight ]:
368.42600

[ Flash Point ]:
289.6ºC

[ Exact Mass ]:
368.17400

[ PSA ]:
67.87000

[ LogP ]:
2.13840

[ Index of Refraction ]:
1.635

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
Missing Phrase - N15.00950417

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Related Compounds

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