4-Pregnene-3,11,20-trione
Names
[ CAS No. ]:
516-15-4
[ Name ]:
4-Pregnene-3,11,20-trione
[Synonym ]:
EINECS 208-222-1
11-ketoprogesterone
MFCD00021110
Chemical & Physical Properties
[ Density]:
1.14 g/cm3
[ Boiling Point ]:
487.6ºC at 760 mmHg
[ Melting Point ]:
170-175 °C(lit.)
[ Molecular Formula ]:
C21H28O3
[ Molecular Weight ]:
328.44500
[ Flash Point ]:
209.3ºC
[ Exact Mass ]:
328.20400
[ PSA ]:
51.21000
[ LogP ]:
3.90250
[ Index of Refraction ]:
1.55
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU5513000
- CHEMICAL NAME :
- Pregn-4-ene-3,11,20-trione
- CAS REGISTRY NUMBER :
- 516-15-4
- BEILSTEIN REFERENCE NO. :
- 2063775
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H28-O3
- MOLECULAR WEIGHT :
- 328.49
- WISWESSER LINE NOTATION :
- L E5 B666 CV OV MUTJ A1 E1 FV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 2500 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 146,401,1974
Safety Information
[ RTECS ]:
TU5513000