11-Dehydrocorticosterone

Names

[ CAS No. ]:
72-23-1

[ Name ]:
11-Dehydrocorticosterone

[Synonym ]:
Corticosterone,11-dehydro
17-Deoxycortisone
Kendall's compound A
Dehydrocorticosterone
Cortisone,17-deoxy
17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
21-hydroxypregn-4-ene-3,11,20-trione
4-pregnene-21-ol-3,11,20-trione
Corticosterone,dehydro
21-hydroxy-4-pregnene-3,11,20-trione
Dehydrocortocicosterone
11-Dehydrocorticosteron

Biological Activity

[Description]:

11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Sheppard KE, et al. 11Beta-hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. Endocrinology. 2002;143(1):198-204.

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
530ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₈O₄

[ Molecular Weight ]:
344.44500

[ Flash Point ]:
288.4ºC

[ Exact Mass ]:
344.19900

[ PSA ]:
71.44000

[ LogP ]:
2.87490

[ Index of Refraction ]:
1.567

MSDS

Click to get detail MSDS

Precursor & DownStream

Precursor

DownStream

Related Compounds

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