1,1,3,3-Tetramethylurea-d12

Names

[ CAS No. ]:
51219-89-7

[ Name ]:
1,1,3,3-Tetramethylurea-d12

[Synonym ]:
Tetramethylharnstoff-d12
dodecadeuterio-tetramethylurea
tetrakis-trideuteriomethyl-urea
tetramethylurea-d12
MFCD00068364
EINECS 257-062-9

Biological Activity

[Description]:

1,1,3,3-Tetramethylurea-d12 is the deuterium labeled 1,1,3,3-Tetramethylurea[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
0.946g/cm3

[ Boiling Point ]:
174-178ºC

[ Melting Point ]:
1ºC

[ Molecular Formula ]:
C5D12N2O

[ Molecular Weight ]:
128.23600

[ Flash Point ]:
53.9ºC

[ Exact Mass ]:
128.17000

[ PSA ]:
23.55000

[ LogP ]:
0.22960

[ Index of Refraction ]:
1.445

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R61

[ Safety Phrases ]:
S45-S53

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds