3-Bromopropylamine hydrobromide
Names
[ CAS No. ]:
5003-71-4
[ Name ]:
3-Bromopropylamine hydrobromide
[Synonym ]:
MFCD00012912
EINECS 225-675-0
3-Bromopropan-1-amine hydrobromide
3-bromopropan-1-amine,hydrobromide
3-Aminopropyl Bromide Hydrobromide
Chemical & Physical Properties
[ Boiling Point ]:
150.6ºC at 760 mmHg
[ Melting Point ]:
171-172 °C(lit.)
[ Molecular Formula ]:
C3H9Br2N
[ Molecular Weight ]:
218.918
[ Flash Point ]:
44.9ºC
[ Exact Mass ]:
216.910156
[ PSA ]:
26.02000
[ LogP ]:
2.38850
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UH9925000
- CHEMICAL NAME :
- Propylamine, 3-bromo-, hydrobromide
- CAS REGISTRY NUMBER :
- 5003-71-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C3-H8-Br-N.Br-H
- MOLECULAR WEIGHT :
- 218.95
- WISWESSER LINE NOTATION :
- Z3E &EH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 109 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,1117,1977 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1150 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,391,1979
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UH9925000
[ HS Code ]:
2921199090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921199090
[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Sci. Rep. 5 , 13833, (2015)
Pentameric ligand-gated ion channels (pLGICs) are targets of general anesthetics, but molecular mechanisms underlying anesthetic action remain debatable. We found that ELIC, a pLGIC from Erwinia chrys...
Inhibition of tissue-bound semicarbazide-sensitive amine oxidase by two haloamines, 2-bromoethylamine and 3-bromopropylamine.Arch. Biochem. Biophys. 385(1) , 154-61, (2001)
Various mammalian tissues contain membrane-bound amine oxidase termed semicarbazide-sensitive amine oxidase (SSAO). A variety of compounds has been identified as relatively selective SSAO inhibitors, ...
Modification of cysteine.Curr. Protoc. Protein Sci. Chapter 15 , Unit15.1, (2001)
This unit describes a number of methods for modifying cysteine residues of proteins and peptides by reduction and alkylation procedures. A general procedure for alkylation of cysteine residues in a pr...