2-Oxo-2H-pyran-5-carboxylic acid

Names

[ CAS No. ]:
500-05-0

[ Name ]:
2-Oxo-2H-pyran-5-carboxylic acid

[Synonym ]:
2-Pyrone-5-carboxylic acid,2-Oxo-2H-pyran-5-carboxylic acid
2H-Pyran-5-carboxylic acid, 2-oxo-
6-oxopyran-3-carboxylic acid
α-Pyrone-5-carboxylic Acid
2-Oxo-2H-pyran-5-carboxylic acid
Cumalic Acid
Coumalic Acid
EINECS 207-899-0
MFCD00006644

Biological Activity

[Description]:

Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Smith LK, et, al. Flow synthesis of coumalic acid and its derivatization. Department of Chemistry. 2018, 3: 722-732.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
282.4±0.0 °C at 760 mmHg

[ Melting Point ]:
203-205 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₄O₄

[ Molecular Weight ]:
140.094

[ Flash Point ]:
137.3±19.4 °C

[ Exact Mass ]:
140.010956

[ PSA ]:
67.51000

[ LogP ]:
-0.43

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.577

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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