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SBC-115076

Names

[ CAS No. ]:
489415-96-5

[ Name ]:
SBC-115076

[Synonym ]:
4-[4-(Benzyloxy)-3-methylbenzoyl]-3-hydroxy-1-[3-(morpholin-4-yl)propyl]-5-(pyridin-4-yl)-1,5-dihydro-2H-pyrrol-2-one
2H-Pyrrol-2-one, 1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-
4-[4-(Benzyloxy)-3-methylbenzoyl]-3-hydroxy-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one
SBC-115076

Biological Activity

[Description]:

SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases.Target: PCSK9in vivo: SBC-115076 lowers cholesterol levels in mice that are fed high fat diet.

[Related Catalog]:

Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Cardiovascular Disease

[References]

[1]. Abdel-Meguid, et al. Anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases


[Related Small Molecules]

Rapamycin (Sirolimus) | MG-132 | Cycloheximide | 3-Methyladenine | LY294002 | TAK-242 | (+)-JQ1 | SB203580 | Pyrazolanthrone (SP600125) | U0126-EtOH | Actinomycin D | Chloroquine diphosphate | CHIR-99021 (CT99021) | MK-2206 2HCl | Dorsomorphin dihydrochloride

Chemical & Physical Properties

[ Density]:
1.3±0.0 g/cm3

[ Boiling Point ]:
754.2±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H33N3O5

[ Molecular Weight ]:
527.611

[ Flash Point ]:
409.9±0.0 °C

[ Exact Mass ]:
527.242004

[ LogP ]:
3.47

[ Vapour Pressure ]:
0.0±0.0 mmHg at 25°C

[ Index of Refraction ]:
1.624

[ Storage condition ]:
-20℃

Related Compounds

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