1-Naphthylmethanol

Names

[ Name ]:
1-Naphthylmethanol

[Synonym ]:
(1-naphthyl)methanol
1-Naphthalenemethano
1-naphthylenemethanol
RARECHEM AL BD 0090
1-menaphthylalcohol
EINECS 225-324-1
1-Naphthylmethanol
MFCD00004044
naphthalene-1-methanol
1-(hydroxymethyl)naphthalene
1-Naphtylmethanol
naphth-1-yl-methanol
1-naphthyl carbinol
naphthalen-1-ylmethanol
1-Naphthalenemethanol

Biological Activity

[Description]:

1-Naphthalenemethanol is a natural compound the root bark extracts of Annona senegalensis with antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Theophine Chinwuba Okoye, et al. Antimicrobial Effects of a Lipophilic Fraction and Kaurenoic Acid Isolated from the Root Bark Extracts of Annona senegalensis. Evid Based Complement Alternat Med. 2012;2012:831327.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
303.6±0.0 °C at 760 mmHg

[ Melting Point ]:
61-63 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₀O

[ Molecular Weight ]:
158.197

[ Flash Point ]:
154.0±15.1 °C

[ Exact Mass ]:
158.073166

[ PSA ]:
20.23000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.657

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ8880000

CHEMICAL NAME :: 1-Naphthalenemethanol

CAS REGISTRY NUMBER :: 4780-79-4

BEILSTEIN REFERENCE NO. :: 2042532

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H10-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 24,2583,1990

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
QJ8880000

[ HS Code ]:
2906299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2906299090

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Arylsulfotransferase IV catalyzed sulfation of 1-naphthalenemethanol.

Adv. Exp. Med. Biol. 197 , 415-22, (1986)

Assay of purified aryl sulfotransferase suitable for reactions yielding unstable sulfuric acid esters.

Anal. Biochem. 183(2) , 320-4, (1989)

An assay procedure for purified aryl sulfotransferase is described. The method utilizes isocratic paired-ion reverse-phase HPLC analysis of adenosine-3',5'-diphosphate formed in the reaction. Evaluati...

Photodecomposition of 1-naphthaleneacetic acid. Crosby DG and Tang C-S.

J. Agric. Food Chem. 17(6) , 1291-93, (1969)

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.