naphthal

Names

[ CAS No. ]:
66-77-3

[ Name ]:
naphthal

[Synonym ]:
1-NAPHTHYLALDEHYDE
1-Naphthalenecarboxaldehyde
naphthal
I-Naphthaldehyd
1-Naphthaldehdye
Naphthalen-1-carbaldehyd
1-FORMYLNAPHTHALENE
1-ANPHTHALDEHYDE
A-NAPHTHALDEHYDE
naphthalene-1-carboxyaldehyde
EINECS 200-633-4
1-Naphthaldehyde
naphthalene-1-carboxaldehyde
MFCD00004003

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
292.0±0.0 °C at 760 mmHg

[ Melting Point ]:
1-2 °C(lit.)

[ Molecular Formula ]:
C₁₁H₈O

[ Molecular Weight ]:
156.181

[ Flash Point ]:
179.5±5.0 °C

[ Exact Mass ]:
156.057510

[ PSA ]:
17.07000

[ LogP ]:
2.87

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.676

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ0190000

CHEMICAL NAME :: 1-Naphthaldehyde

CAS REGISTRY NUMBER :: 66-77-3

BEILSTEIN REFERENCE NO. :: 0386082

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C11-H8-O

MOLECULAR WEIGHT :: 156.19

WISWESSER LINE NOTATION :: L66J BVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 667 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533568

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 19,964,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >20 mL/kg

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533568 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2697 No. of Facilities: 22 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 112 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S37/39-S26-S24/25-S36/37-S23

[ RIDADR ]:
3082

[ WGK Germany ]:
3

[ RTECS ]:
QJ0190000

[ Packaging Group ]:
III

[ HS Code ]:
2912190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912299000

[ Summary ]:
2912299000. other cyclic aldehydes without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

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Exp. Neurol. 269 , 233-41, (2015)

The role of cannabinoid systems in conditioned fear memory was investigated in streptozotocin (STZ)-induced diabetic mice. The cannabinoid receptor agonist WIN-55,212-2 (1mg/kg, i.p.), when injected i...

Structures and vibrational frequencies of 2-hydroxy-3-methoxy-5-nitrobenzaldehyde and 2-methoxy-1-naphthaldehyde based on density functional theory calculations.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 63(2) , 464-76, (2006)

FT-IR and FT-Raman spectra of 2-hydroxy-3-methoxy-5-nitrobenzaldehyde (HMN) and 2-methoxy-1-naphthaldehyde (MN) have been recorded in the regions 4000-400 cm(-1) and 3500-100 cm(-1), respectively. The...

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Epilepsy Res. 108(10) , 1728-33, (2014)

The influence of WIN 55,212-2 mesylate (WIN) on the anticonvulsant activity and acute neurotoxic potential of clobazam (CLB) and lacosamide (LCM) was studied in the maximal electroshock-induced seizur...