cis-2,3-piperidinedicarboxylic acid

Names

[ Name ]:
cis-2,3-piperidinedicarboxylic acid

[Synonym ]:
cis PDA
2,3-piperidinedicarboxylicacid
CIS-2,3-PIPERIDINE-DICARBOXYLIC ACID
2,3cis-Piperidinedicarboxylicacid
2,3-Piperidinedicarboxylicacid,(2R,3S)-rel
CIS-2,3-PIPERIDINE DICARBOXYLIC ACID--*D EA CONTROLL

Biological Activity

[Description]:

Cis-piperidine-2,3-dicarboxylic acid is a non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Cis-piperidine-2,3-dicarboxylic acid can be used in blocking general excitatory synaptic transmissions[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. Viswanathan S, et al. Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques. Macaque photopic sinusoidal flicker ERG. Doc Ophthalmol. 2002 Sep;105(2):223-42.

Chemical & Physical Properties

[ Density]:
1.363g/cm3

[ Boiling Point ]:
419.4ºC at 760mmHg

[ Molecular Formula ]:
C₇H₁₁NO₄

[ Molecular Weight ]:
173.17

[ Flash Point ]:
207.5ºC

[ Exact Mass ]:
173.06900

[ PSA ]:
86.63000

[ Index of Refraction ]:
1.52

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%