Neocnidilide

Names

[ Name ]:
Neocnidilide

[Synonym ]:
trans-3-Butyl-4,5,6,7-tetrahydrophthalid
(3S,3aR)-(-)-Sedanolide
Neocnidilide
1(3H)-Isobenzofuranone,3-butyl-3a,4,5,6-tetrahydro-,cis-(-)
(3aR)-3c-Butyl-(3ar)-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-on
(3aR)-3c-butyl-(3ar)-3a,4,5,6-tetrahydro-3H-isobenzofuran-1-one

Biological Activity

[Description]:

Neocnidilide is an alkylphthalide, which has the activity of inhibiting the growth of mycotoxin-producing fungi. Neocnidilide also has larvicidal activity against D. melanogaster with a LC50 value of 9.9 μmol/mL[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Xiao-Zhen Jiao, et al. Study of stereoselective synthesis of (+/-)-neocnidilide. J Asian Nat Prod Res. 2003 Sep;5(3):165-9.

[2]. Toshihiko Tsukamoto, et al. Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem. 2005 Jul 13;53(14):5549-53.

Chemical & Physical Properties

[ Density]:
1.03g/cm3

[ Boiling Point ]:
342ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₈O₂

[ Molecular Weight ]:
194.27000

[ Flash Point ]:
142.1ºC

[ Exact Mass ]:
194.13100

[ PSA ]:
26.30000

[ LogP ]:
2.82850

[ Index of Refraction ]:
1.499

Related Compounds

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