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PSB11 hydrochloride

Names

[ CAS No. ]:
453591-58-7

[ Name ]:
PSB11 hydrochloride

[Synonym ]:
(8R)-8-Ethyl-4-methyl-2-phenyl-1,4,7,8-tetrahydro-5H-imidazo[2,1-i]purin-5-one hydrochloride (1:1)
5H-Imidazo[2,1-i]purin-5-one, 8-ethyl-1,4,7,8-tetrahydro-4-methyl-2-phenyl-, (8R)-, hydrochloride (1:1)

Biological Activity

[Description]:

PSB11 hydrochloride is an antagonist with reverse excitatory activity for human A3 Adenosine Receptor with high affinity (Ki=2.3 nM)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[Target]

human A3:2.3 nM (Ki)


[References]

[1]. Müller C E, et al. [3H] 8-Ethyl-4-methyl-2-phenyl-(8R)-4, 5, 7, 8-tetrahydro-1H-imidazo [2, 1-i]-purin-5-one ([3H] PSB-11), a novel high-affinity antagonist radioligand for human A3 adenosine receptors[J]. Bioorganic & medicinal chemistry letters, 2002, 12(3): 501-503.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H18ClN5O

[ Molecular Weight ]:
331.800

[ Exact Mass ]:
331.119995

Related Compounds