453591-58-7

453591-58-7 structure

Name: PSB11 hydrochloride
Chemical Name: PSB 11 hydrochloride
CAS Number: 453591-58-7
Molecular Formula: C₁₆H₁₈ClN₅O
Molecular Weight: 331.800
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2021-05-14 20:17:29
Modify Date: 2024-01-10 13:54:29
PSB11 hydrochloride is an antagonist with reverse excitatory activity for human A3 Adenosine Receptor with high affinity (Ki=2.3 nM)[1].

Name	PSB 11 hydrochloride
Synonyms	(8R)-8-Ethyl-4-methyl-2-phenyl-1,4,7,8-tetrahydro-5H-imidazo[2,1-i]purin-5-one hydrochloride (1:1) 5H-Imidazo[2,1-i]purin-5-one, 8-ethyl-1,4,7,8-tetrahydro-4-methyl-2-phenyl-, (8R)-, hydrochloride (1:1)

Description	PSB11 hydrochloride is an antagonist with reverse excitatory activity for human A3 Adenosine Receptor with high affinity (Ki=2.3 nM)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	human A3:2.3 nM (Ki)
References	[1]. Müller C E, et al. [3H] 8-Ethyl-4-methyl-2-phenyl-(8R)-4, 5, 7, 8-tetrahydro-1H-imidazo [2, 1-i]-purin-5-one ([3H] PSB-11), a novel high-affinity antagonist radioligand for human A3 adenosine receptors[J]. Bioorganic & medicinal chemistry letters, 2002, 12(3): 501-503.