2-(2-Fluorophenyl)acetic acid
Names
[ CAS No. ]:
451-82-1
[ Name ]:
2-(2-Fluorophenyl)acetic acid
[Synonym ]:
2-Fluorophenyl acetic acid
2-fluorophenylaceticacid
Benzeneacetic acid, 2-fluoro-
MFCD00004315
EINECS 207-196-9
(2-Fluorophenyl)acetic acid
2-(2-Fluorophenyl)acetic acid
2-Fluoro phenyl acetic acid
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
259.6±15.0 °C at 760 mmHg
[ Melting Point ]:
60-62 °C(lit.)
[ Molecular Formula ]:
C8H7FO2
[ Molecular Weight ]:
154.14
[ Flash Point ]:
110.8±20.4 °C
[ Exact Mass ]:
154.043015
[ PSA ]:
37.30000
[ LogP ]:
1.56
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.529
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Med. Chem. (Los Angeles) 1(102) , (2011)
Eight halogenated N,N'-diphenethylethylenediamines were synthesized, characterized and evaluated for 1 receptor binding affinity in vitro. Measurements of lipophilicity also were obtained. The substit...
Boron trifluoride-induced reactions of phenylglycidyl ethers: a convenient synthesis of enantiopure, stereodefined fluorohydrins. Islas-González G, et al.Tetrahedron Lett. 45(33) , 6337-41, (2004)
Efficient synthesis of bicyclic oxazolino- and thiazolino[3,2-c]pyrimidine-5,7-diones and its application to the synthesis of GnRH antagonists.
Bioorg. Med. Chem. Lett. 15(5) , 1407-11, (2005)
Treatment of various 2-methyl oxazolines or thiazolines with chlorocarbonyl isocyanate gives the corresponding bicyclic oxazolino- or thiazolino[3,2-c]pyrimidin-5,7-dione derivatives in very good yiel...