2-Fluorophenol

Names

[ CAS No. ]:
367-12-4

[ Name ]:
2-Fluorophenol

[Synonym ]:
Phenol, o-fluoro-
2-fluoro-pheno
Phenol,2-fluoro
2-fluoro-phenol
ortho-fluorophenol
Phenol,o-fluoro
o-Fluorophenol
1-Fluoro-2-hydroxybenzene
o-fluoro-pheno
2-Fluorophenol
Phenol, 2-fluoro-
2-Flurophenol
SL4530000 [RTECS]
EINECS 206-681-2
2-fluorophenyl
QR BF
fluorophenol
MFCD00002155

Biological Activity

[Description]:

2-Fluorophenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
151.5±0.0 °C at 760 mmHg

[ Melting Point ]:
16.1 °C(lit.)

[ Molecular Formula ]:
C₆H₅FO

[ Molecular Weight ]:
112.102

[ Flash Point ]:
46.7±0.0 °C

[ Exact Mass ]:
112.032440

[ PSA ]:
20.23000

[ LogP ]:
1.71

[ Vapour Pressure ]:
2.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
Flammables area

[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL4530000

CHEMICAL NAME :: Phenol, o-fluoro-

CAS REGISTRY NUMBER :: 367-12-4

BEILSTEIN REFERENCE NO. :: 1905112

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H5-F-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 537 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R20/21/22;R36/37/38

[ Safety Phrases ]:
S28-S36/37-S36/37/39-S26-S16-S24/25-S23-S53

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SL4530000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29081000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Analysis of the association of cobalt(III) chelates with fluorine-containing phenols in supercritical carbon dioxide.

Talanta 146 , 789-94, (2015)

The solubilities of several cobalt(III) chelates (CoL3) with in supercritical carbon dioxide (SC-CO2) were investigated in the presence of fluorine- and trifluoromethyl-substituted phenols (PhOH) usin...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

The many roles for fluorine in medicinal chemistry.

J. Med. Chem. 51 , 4359-69, (2008)